Emotion appraisal is modulated by the genetic polymorphism of the serotonin transporter

Erika Szily, John Bowen, Zsolt Unoka, Lajos Simon, S. Kéri

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

We investigated the relationship between the genetic polymorphism of the promoter of the serotonin transporter gene (SLC64A) and emotion appraisal profiles for fear, sadness, and joy in 114 healthy volunteers. Results revealed that carriers of the s-allele achieved higher scores than non-carriers for unpleasantness and goal-hindrance but scored lower for coping ability in the case of fear and sadness. There were no such differences in the case of joy. These results indicate that the s-allele of the serotonin transporter gene is associated with a vulnerable cognitive style related to the appraisal of negative emotions.

Original languageEnglish
Pages (from-to)819-822
Number of pages4
JournalJournal of Neural Transmission
Volume115
Issue number6
DOIs
Publication statusPublished - Jun 2008

Fingerprint

Serotonin Plasma Membrane Transport Proteins
Genetic Polymorphisms
Fear
Emotions
Alleles
Aptitude
Genetic Promoter Regions
Genes
Healthy Volunteers

Keywords

  • Appraisal
  • Emotion
  • Genetics
  • Polymorphism
  • Serotonin transporter

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Emotion appraisal is modulated by the genetic polymorphism of the serotonin transporter. / Szily, Erika; Bowen, John; Unoka, Zsolt; Simon, Lajos; Kéri, S.

In: Journal of Neural Transmission, Vol. 115, No. 6, 06.2008, p. 819-822.

Research output: Contribution to journalArticle

Szily, Erika ; Bowen, John ; Unoka, Zsolt ; Simon, Lajos ; Kéri, S. / Emotion appraisal is modulated by the genetic polymorphism of the serotonin transporter. In: Journal of Neural Transmission. 2008 ; Vol. 115, No. 6. pp. 819-822.
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