Emerging role of microRNAs in liver diseases

Shashi Bala, Miguel Marcos, G. Szabó

Research output: Contribution to journalReview article

112 Citations (Scopus)

Abstract

MicroRNAs are a class of small non-coding RNAs that are found in plants, animals, and some viruses. They modulate the gene function at the post-transcriptional level and act as a fine tuner of various processes, such as development, proliferation, cell signaling, and apoptosis. They are associated with different types and stages of cancer. Recent studies have shown the involvement of microRNAs in liver diseases caused by various factors, such as Hepatitis C, Hepatitis B, metabolic disorders, and by drug abuse. This review highlights the role of microRNAs in liver diseases and their potential use as therapeutic molecules.

Original languageEnglish
Pages (from-to)5633-5640
Number of pages8
JournalWorld Journal of Gastroenterology
Volume15
Issue number45
DOIs
Publication statusPublished - Dec 7 2009

Fingerprint

MicroRNAs
Liver Diseases
Small Untranslated RNA
Therapeutic Uses
Hepatitis C
Hepatitis B
Substance-Related Disorders
Cell Proliferation
Apoptosis
Viruses
Genes
Neoplasms

Keywords

  • Cirrhosis
  • Fatty liver
  • Fibrosis
  • Hepatitis
  • MicroRNA

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Emerging role of microRNAs in liver diseases. / Bala, Shashi; Marcos, Miguel; Szabó, G.

In: World Journal of Gastroenterology, Vol. 15, No. 45, 07.12.2009, p. 5633-5640.

Research output: Contribution to journalReview article

Bala, Shashi ; Marcos, Miguel ; Szabó, G. / Emerging role of microRNAs in liver diseases. In: World Journal of Gastroenterology. 2009 ; Vol. 15, No. 45. pp. 5633-5640.
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