Emerging horizons for tick-borne pathogens: From the 'one pathogen-one disease' vision to the pathobiome paradigm

Muriel Vayssier-Taussat, Maria Kazimirova, Zdenek Hubalek, Sándor Hornok, Robert Farkas, Jean François Cosson, Sarah Bonnet, Gwenaël Vourch, Patrick Gasqui, Andrei Daniel Mihalca, Olivier Plantard, Cornelia Silaghi, Sally Cutler, Annapaola Rizzoli

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Ticks, as vectors of several notorious zoonotic pathogens, represent an important and increasing threat for human and animal health in Europe. Recent applications of new technology revealed the complexity of the tick microbiome, which may affect its vectorial capacity. Appreciation of these complex systems is expanding our understanding of tick-borne pathogens, leading us to evolve a more integrated view that embraces the 'pathobiome'; the pathogenic agent integrated within its abiotic and biotic environments. In this review, we will explore how this new vision will revolutionize our understanding of tick-borne diseases. We will discuss the implications in terms of future research approaches that will enable us to efficiently prevent and control the threat posed by ticks.

Original languageEnglish
Pages (from-to)2033-2043
Number of pages11
JournalFuture Microbiology
Volume10
Issue number12
DOIs
Publication statusPublished - Dec 1 2015

Fingerprint

Ticks
Tick-Borne Diseases
Microbiota
Zoonoses
Technology
Health

Keywords

  • co-infections
  • emerging diseases
  • Ixodes ricinus
  • new paradigm
  • next-generation sequencing
  • pathobiome
  • unknown pathogens
  • vector competence
  • zoonoses

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Emerging horizons for tick-borne pathogens : From the 'one pathogen-one disease' vision to the pathobiome paradigm. / Vayssier-Taussat, Muriel; Kazimirova, Maria; Hubalek, Zdenek; Hornok, Sándor; Farkas, Robert; Cosson, Jean François; Bonnet, Sarah; Vourch, Gwenaël; Gasqui, Patrick; Mihalca, Andrei Daniel; Plantard, Olivier; Silaghi, Cornelia; Cutler, Sally; Rizzoli, Annapaola.

In: Future Microbiology, Vol. 10, No. 12, 01.12.2015, p. 2033-2043.

Research output: Contribution to journalArticle

Vayssier-Taussat, M, Kazimirova, M, Hubalek, Z, Hornok, S, Farkas, R, Cosson, JF, Bonnet, S, Vourch, G, Gasqui, P, Mihalca, AD, Plantard, O, Silaghi, C, Cutler, S & Rizzoli, A 2015, 'Emerging horizons for tick-borne pathogens: From the 'one pathogen-one disease' vision to the pathobiome paradigm', Future Microbiology, vol. 10, no. 12, pp. 2033-2043. https://doi.org/10.2217/fmb.15.114
Vayssier-Taussat, Muriel ; Kazimirova, Maria ; Hubalek, Zdenek ; Hornok, Sándor ; Farkas, Robert ; Cosson, Jean François ; Bonnet, Sarah ; Vourch, Gwenaël ; Gasqui, Patrick ; Mihalca, Andrei Daniel ; Plantard, Olivier ; Silaghi, Cornelia ; Cutler, Sally ; Rizzoli, Annapaola. / Emerging horizons for tick-borne pathogens : From the 'one pathogen-one disease' vision to the pathobiome paradigm. In: Future Microbiology. 2015 ; Vol. 10, No. 12. pp. 2033-2043.
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