Emergence of production of the brain peptides

B. Mess, R. Józsa, J. Horváth, G. Sétáló

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The onset of the synthesis of the releasing and inhibiting hormones, associated with their identified primary structures (LHRH, somatostatin), has been studied successfully in some vertebrates. It is known from radioimmunoassay and immunohistological studies that the synthesis of LHRH, TRH and somatostatin begins in the brain of different mammalian species (rat, mouse, guinea pig, man) during embryonic life. Much less is known about this phenomenon in birds. According to very scarce immunohistological data, the first traces of identifiable LHRH appear in the brain of the chicken on day 5 1 2 of embryonic life, while somatostatin appears on the 12th embryonic day. It is remarkable, both in mammals and birds, that the onset of trophic hormone secretion usually proceeds that of the releasing and inhibiting hormones. This would indicate that the releasing and inhibiting hormones do not play a significant role in the embryonic differentiation and induction of hormone secretion of the fetal adenohypophysis.

Original languageEnglish
Pages (from-to)195-204
Number of pages10
JournalPsychoneuroendocrinology
Volume8
Issue number2
DOIs
Publication statusPublished - 1983

Fingerprint

Hormones
Peptides
Somatostatin
Gonadotropin-Releasing Hormone
Brain
Birds
Embryonic Induction
Anterior Pituitary Gland
Radioimmunoassay
Vertebrates
Mammals
Chickens
Guinea Pigs

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Psychiatry and Mental health
  • Biological Psychiatry
  • Endocrine and Autonomic Systems
  • Psychology(all)

Cite this

Emergence of production of the brain peptides. / Mess, B.; Józsa, R.; Horváth, J.; Sétáló, G.

In: Psychoneuroendocrinology, Vol. 8, No. 2, 1983, p. 195-204.

Research output: Contribution to journalArticle

Mess, B. ; Józsa, R. ; Horváth, J. ; Sétáló, G. / Emergence of production of the brain peptides. In: Psychoneuroendocrinology. 1983 ; Vol. 8, No. 2. pp. 195-204.
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