Emergence of OXA-162-producing klebsiella pneumoniae in Hungary

Laura Jánvári, Ivelina Damjanova, Andrea Lázár, Katalin Rácz, Béla Kocsis, Edit Urbán, Ákos TÓth

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

In August 2012, 2 carbapenem-resistant Klebsiella pneumoniae isolates from the University of Szeged were submitted to the National Reference Laboratory at the National Centre for Epidemiology to confirm the carbapenem resistance mechanism. PCR assays and sequencing revealed that the isolates harboured the blaOXA-162 carbapenemase gene, a very recently described variant of OXA-48, and the blaCTX-M-15 extended-spectrum β-lactamase gene. The isolates had indistinguishable PFGE patterns and belonged to sequence type ST15. To the best of our knowledge, this is the first description of OXA-48-like carbapenemase-producing bacteria in Hungary and of an OXA-162-type carbapenemase gene in the K. pneumoniae ST15 clone.

Original languageEnglish
Pages (from-to)320-324
Number of pages5
JournalScandinavian Journal of Infectious Diseases
Volume46
Issue number4
DOIs
Publication statusPublished - Jan 1 2014

Keywords

  • Carbapenemase
  • Hungary
  • Klebsiella pneumoniae
  • OXA-162
  • ST15

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

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