Elimination of UV-resistance inducing effect of R46 R factor by 5-fluorouracil.

I. Francia, Z. Hernádi, M. Szabolcs, F. Hernádi

Research output: Contribution to journalArticle

Abstract

R-factor curing capacity of 5-fluorouracil (5-FU) was studied. Well detectable increase in UV-resistance was found in E. coli K12 AB1157 strain and its recB-, recC-, recF- mutants harbouring R46 R-factor. After treatment with 5-FU, these strains lost not only the antibiotic resistance coded for R46 R-factor but their UV-radioresistance, as well.

Original languageEnglish
Pages (from-to)491-496
Number of pages6
JournalActa Biochimica et Biophysica Hungarica
Volume22
Issue number4
Publication statusPublished - 1987

Fingerprint

R388
R Factors
Fluorouracil
Escherichia coli K12
Microbial Drug Resistance
Escherichia coli
Curing
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics

Cite this

Elimination of UV-resistance inducing effect of R46 R factor by 5-fluorouracil. / Francia, I.; Hernádi, Z.; Szabolcs, M.; Hernádi, F.

In: Acta Biochimica et Biophysica Hungarica, Vol. 22, No. 4, 1987, p. 491-496.

Research output: Contribution to journalArticle

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