Elevated expression of Cu, Zn-SOD and Mn-SOD mRNA in inflamed dental pulp tissue

C. Bödör, A. Matolcsy, M. Bernáth

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Aim: To determine the mRNA expression levels of copper-zinc superoxide dismutase (Cu, Zn-SOD) and manganese SOD (Mn-SOD) in healthy and inflamed human dental pulp tissue. Methodology: Sixteen patients with symptomatic irreversible pulpitis (eight females and eight males) were selected for study. Normal healthy pulps were removed from extracted mandibular third molar teeth from 10 systemically healthy individuals (six females and four males). QRT-PCR analysis of Cu, Zn-SOD and Mn-SOD mRNA expression was carried out in 16 cases of irreversible pulpitis and in 10 cases of systemically healthy donors. The Shapiro-Wilk's test was used to test the normality of data, whereas the Mann-Whitney U-test was used to evaluate the significance of the differences between groups. Differences in the expression levels were considered to be statistically significant for P-values

Original languageEnglish
Pages (from-to)128-132
Number of pages5
JournalInternational Endodontic Journal
Volume40
Issue number2
DOIs
Publication statusPublished - Feb 2007

Fingerprint

Pulpitis
Dental Pulp
Manganese
Messenger RNA
Third Molar
Nonparametric Statistics
Zinc
Copper
Tooth
Tissue Donors
Polymerase Chain Reaction

Keywords

  • Inflammation
  • Irreversible pulpitis
  • Superoxide dismutase

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Elevated expression of Cu, Zn-SOD and Mn-SOD mRNA in inflamed dental pulp tissue. / Bödör, C.; Matolcsy, A.; Bernáth, M.

In: International Endodontic Journal, Vol. 40, No. 2, 02.2007, p. 128-132.

Research output: Contribution to journalArticle

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