Elektronenmikroskopische Untersuchungen am Organon vasculosum laminae terminalis der Ratte

Translated title of the contribution: Electron microscopical investigation of the organon vasculosum laminae terminalis (OVLT) (Supraoptic crest) in the rat

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

OVLT is that part of the terminal plate which is characterized by its rich vascular supply. The brain surface covered by a basement membrane forms deep, cleft-like invaginations containing vessels and connective tissue elements. These connective tissue spaces dividing into 0.1 to 0.2 μ end branches are parts of a labyrinthic system in the interior of the organ. The vessels, mostly of the capillary type, are situated in the main clefts; their endothelium often shows fenestration. Some of the capillaries may approach the ventricle to such an extent that they are separated from it by a single ependymal cell. The supporting apparatus of the OVLT is mainly represented by elongated ependymal cells. Their long basal processes traverse the terminal plate to take part with their foot-like endings in the formation of the brain surface and that of the connective tissue spaces. Groups of special ependymal cells often exhibiting cilia may occur in the interior of the organ. Glial cells are mainly represented by astrocytes. The so-called parenchymal cells described in the light microscopy can be identified as small, primitive neurons. A great part of the nerve fibres in the OVLT contains granulated vesicles the diameter of which varies between 650 and 950 Å. The nerve fibres are mainly running vertically between the ependymal processes while at their terminal portion they assume a parallel course to the ependymal processes and end with them at the margin of the connective tissue spaces. Besides granulated vesicles, these free axon terminals contain numerous synaptic-like vesicles and several mitochondria. Some of the free terminals may occur also on the outer surface of the OVLT. The possible functions of the organ are discussed on the basis of the present findings. The hypothesis is raised that - similarly to the median eminence - humoral controlling factors may be released into the vessels. This hypothesis seems to be supported by the presence of free axon terminals containing granulated and synaptic vesicles and the existence of numerous, partly "fenestrated" capillaries draining the connective tissue spaces.

Original languageGerman
Pages (from-to)483-506
Number of pages24
JournalZeitschrift für Zellforschung und Mikroskopische Anatomie
Volume102
Issue number4
DOIs
Publication statusPublished - Dec 1969

Fingerprint

Connective Tissue
Rats
Electrons
Tissue
Synaptic Vesicles
Presynaptic Terminals
Nerve Fibers
Brain
Median Eminence
Mitochondria
Fibers
Cilia
Basement Membrane
Neuroglia
Astrocytes
Running
Neurons
Endothelium
Optical microscopy
Blood Vessels

Keywords

  • Electron microscopy
  • Laminae terminalis
  • Organon vasculosum

ASJC Scopus subject areas

  • Anatomy
  • Clinical Biochemistry
  • Cell Biology
  • Medicine(all)

Cite this

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title = "Elektronenmikroskopische Untersuchungen am Organon vasculosum laminae terminalis der Ratte",
abstract = "OVLT is that part of the terminal plate which is characterized by its rich vascular supply. The brain surface covered by a basement membrane forms deep, cleft-like invaginations containing vessels and connective tissue elements. These connective tissue spaces dividing into 0.1 to 0.2 μ end branches are parts of a labyrinthic system in the interior of the organ. The vessels, mostly of the capillary type, are situated in the main clefts; their endothelium often shows fenestration. Some of the capillaries may approach the ventricle to such an extent that they are separated from it by a single ependymal cell. The supporting apparatus of the OVLT is mainly represented by elongated ependymal cells. Their long basal processes traverse the terminal plate to take part with their foot-like endings in the formation of the brain surface and that of the connective tissue spaces. Groups of special ependymal cells often exhibiting cilia may occur in the interior of the organ. Glial cells are mainly represented by astrocytes. The so-called parenchymal cells described in the light microscopy can be identified as small, primitive neurons. A great part of the nerve fibres in the OVLT contains granulated vesicles the diameter of which varies between 650 and 950 {\AA}. The nerve fibres are mainly running vertically between the ependymal processes while at their terminal portion they assume a parallel course to the ependymal processes and end with them at the margin of the connective tissue spaces. Besides granulated vesicles, these free axon terminals contain numerous synaptic-like vesicles and several mitochondria. Some of the free terminals may occur also on the outer surface of the OVLT. The possible functions of the organ are discussed on the basis of the present findings. The hypothesis is raised that - similarly to the median eminence - humoral controlling factors may be released into the vessels. This hypothesis seems to be supported by the presence of free axon terminals containing granulated and synaptic vesicles and the existence of numerous, partly {"}fenestrated{"} capillaries draining the connective tissue spaces.",
keywords = "Electron microscopy, Laminae terminalis, Organon vasculosum",
author = "P. R{\"o}hlich and T. Wenger",
year = "1969",
month = "12",
doi = "10.1007/BF00335490",
language = "German",
volume = "102",
pages = "483--506",
journal = "Cell and Tissue Research",
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AU - Röhlich, P.

AU - Wenger, T.

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N2 - OVLT is that part of the terminal plate which is characterized by its rich vascular supply. The brain surface covered by a basement membrane forms deep, cleft-like invaginations containing vessels and connective tissue elements. These connective tissue spaces dividing into 0.1 to 0.2 μ end branches are parts of a labyrinthic system in the interior of the organ. The vessels, mostly of the capillary type, are situated in the main clefts; their endothelium often shows fenestration. Some of the capillaries may approach the ventricle to such an extent that they are separated from it by a single ependymal cell. The supporting apparatus of the OVLT is mainly represented by elongated ependymal cells. Their long basal processes traverse the terminal plate to take part with their foot-like endings in the formation of the brain surface and that of the connective tissue spaces. Groups of special ependymal cells often exhibiting cilia may occur in the interior of the organ. Glial cells are mainly represented by astrocytes. The so-called parenchymal cells described in the light microscopy can be identified as small, primitive neurons. A great part of the nerve fibres in the OVLT contains granulated vesicles the diameter of which varies between 650 and 950 Å. The nerve fibres are mainly running vertically between the ependymal processes while at their terminal portion they assume a parallel course to the ependymal processes and end with them at the margin of the connective tissue spaces. Besides granulated vesicles, these free axon terminals contain numerous synaptic-like vesicles and several mitochondria. Some of the free terminals may occur also on the outer surface of the OVLT. The possible functions of the organ are discussed on the basis of the present findings. The hypothesis is raised that - similarly to the median eminence - humoral controlling factors may be released into the vessels. This hypothesis seems to be supported by the presence of free axon terminals containing granulated and synaptic vesicles and the existence of numerous, partly "fenestrated" capillaries draining the connective tissue spaces.

AB - OVLT is that part of the terminal plate which is characterized by its rich vascular supply. The brain surface covered by a basement membrane forms deep, cleft-like invaginations containing vessels and connective tissue elements. These connective tissue spaces dividing into 0.1 to 0.2 μ end branches are parts of a labyrinthic system in the interior of the organ. The vessels, mostly of the capillary type, are situated in the main clefts; their endothelium often shows fenestration. Some of the capillaries may approach the ventricle to such an extent that they are separated from it by a single ependymal cell. The supporting apparatus of the OVLT is mainly represented by elongated ependymal cells. Their long basal processes traverse the terminal plate to take part with their foot-like endings in the formation of the brain surface and that of the connective tissue spaces. Groups of special ependymal cells often exhibiting cilia may occur in the interior of the organ. Glial cells are mainly represented by astrocytes. The so-called parenchymal cells described in the light microscopy can be identified as small, primitive neurons. A great part of the nerve fibres in the OVLT contains granulated vesicles the diameter of which varies between 650 and 950 Å. The nerve fibres are mainly running vertically between the ependymal processes while at their terminal portion they assume a parallel course to the ependymal processes and end with them at the margin of the connective tissue spaces. Besides granulated vesicles, these free axon terminals contain numerous synaptic-like vesicles and several mitochondria. Some of the free terminals may occur also on the outer surface of the OVLT. The possible functions of the organ are discussed on the basis of the present findings. The hypothesis is raised that - similarly to the median eminence - humoral controlling factors may be released into the vessels. This hypothesis seems to be supported by the presence of free axon terminals containing granulated and synaptic vesicles and the existence of numerous, partly "fenestrated" capillaries draining the connective tissue spaces.

KW - Electron microscopy

KW - Laminae terminalis

KW - Organon vasculosum

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