Out of 54 open renal biopsies performed on children, 17 were selected and studied by light microscopy and electron micrsocopy. Statistical-mathematical analysis of basement membrane thickness-measurments was carried out. It is concluded that electron microscopic investigation of the renal biopsy material is required in selected cases involving diagnostic or therapeutic problems. In nephrotic syndrome it may help above all to separate minimal changes from early forms of glomerular lesion of the focal sclerosing type. Electron microscopy can also be useful in any of the mono- and oligosymptomatic renal diseases. In those cases only electron microscopy makes it possible to provide exact morphologic diagnosis which is necessary to the proper therapy.
|Number of pages||15|
|Publication status||Published - Dec 1 1977|
ASJC Scopus subject areas
- Pathology and Forensic Medicine