Electron microscopic investigation on the zona glomerulosa of rats after treatment with heparin and potassium

Gy Lustyik, J. Szabo, E. Gláz, R. Kiss

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The adrenal zona glomerulosa of rats was investigated by means of electron microscopy after stimulation with potassium and suppression with heparin. Both in treated and control animals two types of mitochondria - one with tubular and the other with tubulosaccular cristae - were found. Stimulation with potassium increased the amount of mitochondria with tubular cristae, heparin treatment caused a simplification in the structure of the tubulosaccular cristae. It is assumed that these two mitochondrium-populations contain different enzyme systems, which catalyze the different step-series of aldosterone biosynthesis. On the basis of cytoplasmic density one could distinguish dark and light cells in the zona glomerulosa of control rats only; but they were absent in both groups of treated animals. The density of these cells probably did not depend on their metabolic activity, but rather on their hormone storage.

Original languageEnglish
Pages (from-to)189-197
Number of pages9
JournalExperimental Pathology
Volume13
Issue number4-5
Publication statusPublished - 1977

Fingerprint

Zona Glomerulosa
Mitochondria
Heparin
Rats
Potassium
Animals
Rat control
Electrons
Biosynthesis
Aldosterone
Electron microscopy
Hormones
Electron Microscopy
Enzymes
Cell Count
Population

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Electron microscopic investigation on the zona glomerulosa of rats after treatment with heparin and potassium. / Lustyik, Gy; Szabo, J.; Gláz, E.; Kiss, R.

In: Experimental Pathology, Vol. 13, No. 4-5, 1977, p. 189-197.

Research output: Contribution to journalArticle

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