Electron-cytochemical detection of endogenous nickel in the myocardium in acute carbon monoxide poisoning - Applicability of a new cytochemical technique in forensic medicine

I. Balogh, E. Somogyi, P. Sótónyi, G. Pogátsa, G. Rubanyi, E. Bellus

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

After acute carbon monoxide poisoning (inhalation, dogs; perfusion, rats; postmortem, humans) endogenous nickel was cytochemically detected in heart muscle by dimethylglioxime reaction. Dimethylglioxime cytochemical reaction, in each case at the COHb level, was always positive in experiments and in postmortem samples. A nickel ion accumulation in the heart muscle above 30 rel.% of COHb was suggested. A possible role of nickel ion in the pathomechanism of the acute carbon monoxide poisoning was supposed. This dimethylglioxime cytochemical technique is applicable in forensic medical practice, primarily because it is not disturbed by autolysis.

Original languageEnglish
Pages (from-to)7-14
Number of pages8
JournalZeitschrift für Rechtsmedizin
Volume90
Issue number1
DOIs
Publication statusPublished - Mar 1983

Fingerprint

Carbon Monoxide Poisoning
forensic medicine
Forensic Medicine
Nickel
Myocardium
Electrons
medical practice
Ions
Autolysis
Inhalation
experiment
Perfusion
Dogs

Keywords

  • Acute carbon monoxide
  • Nickel cytochemistry
  • Poisoning, heart muscle

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Anatomy

Cite this

Electron-cytochemical detection of endogenous nickel in the myocardium in acute carbon monoxide poisoning - Applicability of a new cytochemical technique in forensic medicine. / Balogh, I.; Somogyi, E.; Sótónyi, P.; Pogátsa, G.; Rubanyi, G.; Bellus, E.

In: Zeitschrift für Rechtsmedizin, Vol. 90, No. 1, 03.1983, p. 7-14.

Research output: Contribution to journalArticle

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AU - Bellus, E.

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