Melanoma-bo″ráttétek elektrokemoterápiája

Translated title of the contribution: Electrochemotherapy of melanoma cutaneous metastases

Erika Kis, Ilona Szegesdi, Henriette Ocsai, R. Gyulai, L. Kemény, J. Oláh

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Electrochemotherapy is an effective treatment of cutaneous and subcutaneous metastases in patients with malignant melanoma. During the treatment, electric pulses are applied to tumor nodules to deliver non-permeante or poorly permeante chemotherapeutic agents into the cells thereby increasing local cytotoxicity of anticancer drugs. Methods: In 7 patients 81 cutaneous and subcutaneous melanoma metastases were treated with electrochemotherapy. All treatments were performed under general anesthesia using intravenous bleomycin injection. Median follow-up was 218 days. Results: Complete response rate was 25%, partial response rate was 43%. We observed no change in 26%, and progressive disease in 6%. Conclusions: Electrochemotherapy is a simple and effective treatment of single or multiple cutaneous and subcutaneous metastases of melanoma, with minimal side effects. Our results confirm the results of recently published studies that the treatment used for palliation has clinical benefit and impact on the quality of life.

Original languageHungarian
Pages (from-to)96-101
Number of pages6
JournalOrvosi Hetilap
Volume151
Issue number3
DOIs
Publication statusPublished - Jan 1 2010

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Electrochemotherapy
Melanoma
Neoplasm Metastasis
Skin
Therapeutics
Bleomycin
Intravenous Injections
General Anesthesia
Quality of Life
Pharmaceutical Preparations
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Melanoma-bo″ráttétek elektrokemoterápiája. / Kis, Erika; Szegesdi, Ilona; Ocsai, Henriette; Gyulai, R.; Kemény, L.; Oláh, J.

In: Orvosi Hetilap, Vol. 151, No. 3, 01.01.2010, p. 96-101.

Research output: Contribution to journalArticle

Kis, Erika ; Szegesdi, Ilona ; Ocsai, Henriette ; Gyulai, R. ; Kemény, L. ; Oláh, J. / Melanoma-bo″ráttétek elektrokemoterápiája. In: Orvosi Hetilap. 2010 ; Vol. 151, No. 3. pp. 96-101.
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