Electrical stimulation of the median eminence in rats, changes in catecholamine content and in plasma prolactin and growth hormone concentrations

M. I.K. Fekete, J. P. Herman, B. Kanyicska, G. B. Makara

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Effects of field stimulation of the medial basal hypothalamus (MBH) and coaxial stimulation of the median eminence was studied on the catecholamine and DOPAC levels of the median eminence and on the prolactin and growth hormone release. The field stimulation induced an increased prolactin and growth hormone secretion without altering the catecholamine and DOPAC level. The direct electrical stimulation of the median eminence reduced the noradrenaline and dopamine content without significant changes in DOPAC concentration and in hormone secretions. It is concluded that (1) variations of DOPAC content are inadequate indicators of neuronal activity in the median eminence; (2) the multiple interaction of the stimulated neurons in the median eminence may mask the expected biochemical and hormonal responses to electrical stimulation.

Original languageEnglish
Pages (from-to)929-933
Number of pages5
JournalLife Sciences
Volume27
Issue number11
DOIs
Publication statusPublished - Jan 1 1980

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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