Electrical stimulation in the rat of the supraoptic nucleus: Failure to alter plasma corticosterone after surgical lesioning of the paraventricular nucleus

G. Makara, F. A. Antoni, E. Stark

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Electrical stimulation of the supraoptic nucleus (SON) for 3 min in dexamethasone-morphine-pentobarbital-pretreated rats raised the plasma level of corticosterone; 4 dats after placing a surgical lesion in the hypothalamic paraventricular nuclei (PVN) electrical stimulation of the SON failed to change the plasma level of corticosterone. We suggest that nerve fibres originating in or near the PVN that pass near the SON are likely to contain corticotropin releasing factor and elicit the release of ACTH following electrical stimulation.

Original languageEnglish
Pages (from-to)269-273
Number of pages5
JournalNeuroscience Letters
Volume30
Issue number3
DOIs
Publication statusPublished - Jun 30 1982

Fingerprint

Supraoptic Nucleus
Paraventricular Hypothalamic Nucleus
Corticosterone
Electric Stimulation
Corticotropin-Releasing Hormone
Pentobarbital
Nerve Fibers
Adrenocorticotropic Hormone
Morphine
Dexamethasone

Keywords

  • ACTH
  • corticoliberin
  • corticosterone
  • corticotropin releasing factor
  • electrical stimulation
  • hypothalamus

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Electrical stimulation in the rat of the supraoptic nucleus : Failure to alter plasma corticosterone after surgical lesioning of the paraventricular nucleus. / Makara, G.; Antoni, F. A.; Stark, E.

In: Neuroscience Letters, Vol. 30, No. 3, 30.06.1982, p. 269-273.

Research output: Contribution to journalArticle

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