Elastic staining does not assist detection of venous invasion in cutaneous melanoma

István Sejben, Lajos Kocsis, László Török, G. Cserni

Research output: Contribution to journalArticle

Abstract

The aim of the present study was to determine the benefit of orcein elastic staining of primary cutaneous melanoma specimens in detecting venous invasion. Primary cutaneous melanomas in vertical growth phase were assessed for vascular invasion. All tumour blocks were stained with haematoxylin and eosin (H&E) and orcein. The cases were reviewed by two pathologists. Vascular invasion was not identified more frequently on orcein stained slides than on H&E stained ones. Elastosis and periappendiceal elastic fibres interfered with vascular invasion detection with elastic staining. Based on our study, we conclude that elastic stains such as orcein do not improve the detection rate of venous invasion in primary cutaneous melanomas.

Original languageEnglish
Pages (from-to)51-53
Number of pages3
JournalPathology Research and Practice
Volume212
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

Fingerprint

Melanoma
Staining and Labeling
Blood Vessels
Skin
Elastic Tissue
Hematoxylin
Eosine Yellowish-(YS)
Coloring Agents
PAcein
Growth
Neoplasms

Keywords

  • Elastic stain
  • Melanoma
  • Orcein
  • Venous invasion

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Cell Biology

Cite this

Elastic staining does not assist detection of venous invasion in cutaneous melanoma. / Sejben, István; Kocsis, Lajos; Török, László; Cserni, G.

In: Pathology Research and Practice, Vol. 212, No. 1, 01.01.2016, p. 51-53.

Research output: Contribution to journalArticle

Sejben, István ; Kocsis, Lajos ; Török, László ; Cserni, G. / Elastic staining does not assist detection of venous invasion in cutaneous melanoma. In: Pathology Research and Practice. 2016 ; Vol. 212, No. 1. pp. 51-53.
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