Elaboration of a novel type of interglycosidic linkage: Syntheses of disulfide disaccharides

László Szilágyi, Tünde Zita Illyés, P. Herczegh

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Asymmetric non-reducing disaccharides containing an interglycosidic disulfide linkage were synthesised under mild conditions through reaction of tetraacetyl-β-D-glucopyranosyl methanethiolsulfonate with O-acetylated 1-thio-aldopyranoses. The preferred conformation around the -S-S- bond is close to that observed in unconstrained disulfides (-90°).

Original languageEnglish
Pages (from-to)3901-3903
Number of pages3
JournalTetrahedron Letters
Volume42
Issue number23
DOIs
Publication statusPublished - Jun 4 2001

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Disaccharides
Disulfides
Conformations

Keywords

  • Carbohydrates
  • Conformation
  • Disulfides
  • NMR
  • Thiosugars

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Elaboration of a novel type of interglycosidic linkage : Syntheses of disulfide disaccharides. / Szilágyi, László; Illyés, Tünde Zita; Herczegh, P.

In: Tetrahedron Letters, Vol. 42, No. 23, 04.06.2001, p. 3901-3903.

Research output: Contribution to journalArticle

Szilágyi, László ; Illyés, Tünde Zita ; Herczegh, P. / Elaboration of a novel type of interglycosidic linkage : Syntheses of disulfide disaccharides. In: Tetrahedron Letters. 2001 ; Vol. 42, No. 23. pp. 3901-3903.
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