EGF receptor induction and insulin-EGF overlap in Tetrahymena

G. Csaba, P. Kovács

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Offspring generations of Tetrahymena pretreated (imprinted) with insulin showed a greater binding capacity for the hormone than offspring of untreated ones. The epidermal growth factor (EGF) imprinted for insulin to a greater degree than insulin itself, and vice versa: insulin imprinted for EGF more efficiently than EGF itself. These phenomena can be explained by the overlap of insulin and EGF on one another's receptors in Tetrahymena.

Original languageEnglish
Pages (from-to)718-721
Number of pages4
JournalExperientia
Volume47
Issue number7
DOIs
Publication statusPublished - Jul 1 1991

Keywords

  • EGF
  • Tetrahymena
  • hormonal imprinting
  • insulin
  • receptors

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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