Efficient synthesis of deuterated 1,2,3-triazoles

Zsombor Gonda, Krisztián Lrincz, Zoltán Novák

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

A wide variety of 1-monosubstituted 1,2,3-triazoles were synthesized efficiently via a copper-catalyzed click-reaction between azides and acetylene gas, generated in situ from CaC2 with the addition of H2O or D2O.

Original languageEnglish
Pages (from-to)6275-6277
Number of pages3
JournalTetrahedron Letters
Volume51
Issue number48
DOIs
Publication statusPublished - Dec 1 2010

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Keywords

  • Acetylene
  • Click-reaction
  • Copper
  • Deuterium
  • Triazoles

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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