Efficient synthesis of chromones with alkenyl functionalities by the heck reaction

Tams Patonay, Attila Vasas, Attila Kiss-Szikszai, Artur M.S. Silva, Joś A.S. Cavaleiro

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Abstract

The usefulness of the Heck reaction in the field of chromones has been demonstrated. Bromochromones with the halogen atom in their rings A and B were reacted with various terminal alkenes to give hitherto unknown alkenyl-substituted chromones. Reactivity of the substrates was found to markedly depend on the position of the bromine atom. Under phosphine-free conditions using a phase-transfer catalyst additive (tetrabutylammonium bromide), shorter reaction periods and usually higher yields were obtained.

Original languageEnglish
Pages (from-to)1582-1593
Number of pages12
JournalAustralian Journal of Chemistry
Volume63
Issue number11
DOIs
Publication statusPublished - Dec 9 2010

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ASJC Scopus subject areas

  • Chemistry(all)

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