Efficacy of nizatidine, clarithromycin and bismuth subcitrate therapy for helicobacter pylori eradication in duodenal ulcer patients - A preliminary report

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Abstract

The triple combination of nizatidine, clarithromycin, and bismuth subcitrate resulted in an ulcer healing rate of 98% and an H. pylori eradication rate of 90%. Corresponding 'intention-to-treat' figures were 92% and 84%, respectively. These results suggest that further studies, shorter in duration, using lower dosages, and possibly testing other combinations with a double-blind methodology, are required.

Original languageEnglish
Pages (from-to)249-253
Number of pages5
JournalBritish Journal of Clinical Practice
Volume50
Issue number5
Publication statusPublished - 1996

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Nizatidine
Clarithromycin
Duodenal Ulcer
Helicobacter pylori
Ulcer
Therapeutics
bismuth tripotassium dicitrate

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Efficacy of nizatidine, clarithromycin and bismuth subcitrate therapy for helicobacter pylori eradication in duodenal ulcer patients - A preliminary report",
abstract = "The triple combination of nizatidine, clarithromycin, and bismuth subcitrate resulted in an ulcer healing rate of 98{\%} and an H. pylori eradication rate of 90{\%}. Corresponding 'intention-to-treat' figures were 92{\%} and 84{\%}, respectively. These results suggest that further studies, shorter in duration, using lower dosages, and possibly testing other combinations with a double-blind methodology, are required.",
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