Efficacy of moxidectin (macrocyclic lactone), a broad spectrum endectocide for ruminants and horses, against mature wormpairs attached to the trachea and migrating larvae of Syngamus trachea was studied in experimentally infected chickens (n = 265). In a pilot tolerance trial on 3-week-old chickens, toxic signs appeared from the sc. dose of 16 mg/kg. The intramuscular injection, the oral administration to the crop, and the pour-on applications all proved highly effective against the 5-6-day-old larvae and the 14-15-day-old wormpairs. According to the dose titration, a 0.2 mg/kg single dose attains close to 100% efficacy (Table 1 and 2). Persistent efficacy was shown over a week (Table 3); the actual extension of the prophylactic action seems worthy of further study.
|Translated title of the contribution||Efficacy of moxidectin against syngamus trachea in experimentally infected chickens. Preliminary report|
|Number of pages||3|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - Dec 1 1996|
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