Efficacy of a single 6 mg/kg versus two 3 mg/Kg caspofungin doses for treatment of disseminated candidiasis caused by Candida Albicans in a neutropenic mouse model

S. Bayegan, J. Szilágyi, A. Kemény-Beke, R. Földi, G. Kardos, R. Gesztelyi, B. Juhász, A. Adnan, L. Majoros

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We compared the efficacy of single six mg/kg and 2x3 mg/kg caspofungin doses to the traditional one mg/kg daily against C. albicans in a neutropenic murine model. In lethality experiments, all regimens improved survival (p

Original languageEnglish
Pages (from-to)107-109
Number of pages3
JournalJournal of Chemotherapy
Volume23
Issue number2
Publication statusPublished - Apr 2011

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caspofungin
Candidiasis
Candida albicans

Keywords

  • Caspofungin dosing strategy
  • Fungal tissue burden
  • Lethality
  • Murine model

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Infectious Diseases
  • Oncology
  • Pharmacology

Cite this

Efficacy of a single 6 mg/kg versus two 3 mg/Kg caspofungin doses for treatment of disseminated candidiasis caused by Candida Albicans in a neutropenic mouse model. / Bayegan, S.; Szilágyi, J.; Kemény-Beke, A.; Földi, R.; Kardos, G.; Gesztelyi, R.; Juhász, B.; Adnan, A.; Majoros, L.

In: Journal of Chemotherapy, Vol. 23, No. 2, 04.2011, p. 107-109.

Research output: Contribution to journalArticle

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