Effects of the reaction conditions on the enantio-selective esterification using candiada cylindracea lipase

L. Gubicza, A. Szakács-Schmidt

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Abstract

Parameters influencing the synthetic activity and enantioselectivlty of the Candida cylindracea lipase were investigated. The test reaction was presented through the enantioselective esterification of 2-substituted propionic acids in organic solvents. It was found that both the activity and the enantioselectivity of the lipase could be most effectively influenced by solvent engineering. Since the solvent has a different effect on activity and enantioselectivity of the lipase, selection of the most suitable solvent or solvent mixture is an important optimization question.

Original languageEnglish
Pages (from-to)131-143
Number of pages13
JournalBiocatalysis and Biotransformation
Volume9
Issue number1-4
DOIs
Publication statusPublished - Jan 1 1994

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Keywords

  • Candida cylindracea lipase
  • Enantioselectivity
  • Enzymatic esterification
  • Organic media
  • Synthetic activity

ASJC Scopus subject areas

  • Biotechnology
  • Catalysis
  • Biochemistry

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