Effects of suramin on phagocytes in vitro

S. Sipka, K. Dankó, P. Nagy, V. Taskov, L. Dénes, L. Czirják, G. Szegedi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In the therapeutically important range (100-200 μg/ml), suramin was found to increase the phagocytic activity of human monocytes (measured by the uptake of Saccharomyces cerevisiae and sensitized sheep red blood cells) in vitro. Suramin itself was a chemotactic signal for monocytes and increased the chemiluminescence of neutrophil granulocytes. Suramin seems to act via the ATP-binding P2 receptors of human phagocytes.

Original languageEnglish
Pages (from-to)45-48
Number of pages4
JournalAnnals of Hematology
Volume63
Issue number1
DOIs
Publication statusPublished - Jul 1991

Fingerprint

Suramin
Phagocytes
Monocytes
Luminescence
Granulocytes
Human Activities
Saccharomyces cerevisiae
Sheep
Neutrophils
Adenosine Triphosphate
Erythrocytes
In Vitro Techniques

Keywords

  • Phagocyte
  • Suramin

ASJC Scopus subject areas

  • Hematology

Cite this

Effects of suramin on phagocytes in vitro. / Sipka, S.; Dankó, K.; Nagy, P.; Taskov, V.; Dénes, L.; Czirják, L.; Szegedi, G.

In: Annals of Hematology, Vol. 63, No. 1, 07.1991, p. 45-48.

Research output: Contribution to journalArticle

Sipka, S. ; Dankó, K. ; Nagy, P. ; Taskov, V. ; Dénes, L. ; Czirják, L. ; Szegedi, G. / Effects of suramin on phagocytes in vitro. In: Annals of Hematology. 1991 ; Vol. 63, No. 1. pp. 45-48.
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