Effects of species-dependent differences in action potential shape in setting β-adrenergic-stimulation induced current

Luca Sala, Bence Hegyi, Chiara Bartolucci, Claudia Altomare, Marcella Rocchetti, Gaspare Mostacciuolo, Stefano Severi, Norbert Szentandrassy, Peter P. Nanasi, Antonio Zaza

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

In canine (D) and human, but not guinea pig (GP), ventricular myocytes, a spike-and-dome profile (SaD), supported by Ito, characterizes ventricular repolarization. β-adrenergic stimulation (by isoprenaline, ISO) shortens action potential (AP) duration (APD) in D (and human) myocytes, but prolongs it in GP ones.

Original languageEnglish
Title of host publicationComputing in Cardiology 2013, CinC 2013
Pages381-384
Number of pages4
Publication statusPublished - Dec 1 2013
Event2013 40th Computing in Cardiology Conference, CinC 2013 - Zaragoza, Spain
Duration: Sep 22 2013Sep 25 2013

Publication series

NameComputing in Cardiology
Volume40
ISSN (Print)2325-8861
ISSN (Electronic)2325-887X

Other

Other2013 40th Computing in Cardiology Conference, CinC 2013
CountrySpain
CityZaragoza
Period9/22/139/25/13

ASJC Scopus subject areas

  • Computer Science(all)
  • Cardiology and Cardiovascular Medicine

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    Sala, L., Hegyi, B., Bartolucci, C., Altomare, C., Rocchetti, M., Mostacciuolo, G., Severi, S., Szentandrassy, N., Nanasi, P. P., & Zaza, A. (2013). Effects of species-dependent differences in action potential shape in setting β-adrenergic-stimulation induced current. In Computing in Cardiology 2013, CinC 2013 (pp. 381-384). [6713393] (Computing in Cardiology; Vol. 40).