Background: The glycerol from biodiesel as a valuable by-product can be used as food supplements in feed for animals. We investigated the effect of this by-product on metabolism in mice. Materials and Methods: CBA/CA mice were administered purified glycerol products (called SZME3) for 3, 6 and 24 hours. After dietary exposure, gene expressions of cytochrome P450, family 1, subfamily a polypeptide 1 (Cyp1a1) and cytochrome P450, family 2, subfamily e, polypeptide 1 (Cyp2e1) were analysed in liver. Results: SZME3 induced an up-regulation of both genes in both genders after three hours' administration. After longer administration of SZME3, the expression of genes became similar to that of the controls. Conclusion: Based upon our data SZME3 has no long-term effect on oxidative metabolism, it seems not to cause oxidative stress for liver cells.
|Number of pages||4|
|Publication status||Published - Mar 1 2011|
- Gene expression
- Renewable energy
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)