Effects of prandial versus fasting glycemia on cardiovascular outcomes in type 2 diabetes: The HEART2D trial

Itamar Raz, G. Jermendy, Peter W F Wilson, Barbara N. Campaigne, Krzysztof Strojek, Lisa Kerr, Irina Kowalska, Zvonko Milicevic, Velimir Bozikov, Scott J. Jacober, Anselm K. Gitt

Research output: Contribution to journalArticle

254 Citations (Scopus)

Abstract

OBJECTIVE - Hyperglycemia and Its Effect After Acute Myocardial Infarction on Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus (HEART2D) is a multinational, randomized, controlled trial designed to compare the effects of prandial versus fasting glycemic control on risk for cardiovascular outcomes in patients with type 2 diabetes after acute myocardial infarction (AMI). RESEARCH DESIGN AND METHODS - Patients (type 2 diabetes, aged 30-75 years) were randomly assigned within 21 days after AMI to the 1) prandial strategy (PRANDIAL) (three premeal doses of insulin lispro targeting 2-h postprandial blood glucose

Original languageEnglish
Pages (from-to)381-386
Number of pages6
JournalDiabetes Care
Volume32
Issue number3
DOIs
Publication statusPublished - Mar 2009

Fingerprint

Type 2 Diabetes Mellitus
Meals
Fasting
Myocardial Infarction
Insulin Lispro
Hyperglycemia
Blood Glucose
Research Design
Randomized Controlled Trials

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialised Nursing

Cite this

Raz, I., Jermendy, G., Wilson, P. W. F., Campaigne, B. N., Strojek, K., Kerr, L., ... Gitt, A. K. (2009). Effects of prandial versus fasting glycemia on cardiovascular outcomes in type 2 diabetes: The HEART2D trial. Diabetes Care, 32(3), 381-386. https://doi.org/10.2337/dc08-1671

Effects of prandial versus fasting glycemia on cardiovascular outcomes in type 2 diabetes : The HEART2D trial. / Raz, Itamar; Jermendy, G.; Wilson, Peter W F; Campaigne, Barbara N.; Strojek, Krzysztof; Kerr, Lisa; Kowalska, Irina; Milicevic, Zvonko; Bozikov, Velimir; Jacober, Scott J.; Gitt, Anselm K.

In: Diabetes Care, Vol. 32, No. 3, 03.2009, p. 381-386.

Research output: Contribution to journalArticle

Raz, I, Jermendy, G, Wilson, PWF, Campaigne, BN, Strojek, K, Kerr, L, Kowalska, I, Milicevic, Z, Bozikov, V, Jacober, SJ & Gitt, AK 2009, 'Effects of prandial versus fasting glycemia on cardiovascular outcomes in type 2 diabetes: The HEART2D trial', Diabetes Care, vol. 32, no. 3, pp. 381-386. https://doi.org/10.2337/dc08-1671
Raz, Itamar ; Jermendy, G. ; Wilson, Peter W F ; Campaigne, Barbara N. ; Strojek, Krzysztof ; Kerr, Lisa ; Kowalska, Irina ; Milicevic, Zvonko ; Bozikov, Velimir ; Jacober, Scott J. ; Gitt, Anselm K. / Effects of prandial versus fasting glycemia on cardiovascular outcomes in type 2 diabetes : The HEART2D trial. In: Diabetes Care. 2009 ; Vol. 32, No. 3. pp. 381-386.
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