Effects of paraquat treatment on fish transaminase molecular subforms

K. Aranka Deér, János Nemcsók, Lász Ió Boross, Béla Szajáni

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The effects of paraquat (PQ; 1,1′-dimethyl-4,4′-bipyridylium dichloride) treatment were investigated in carp, silver carp and wels. The serum glutamic-oxalacetic transaminase (GOT; L-aspartate: 2-oxoglutarate aminotransferase, EC 2.6.1.1.) level was enhanced by 50% at 1 ppm exposure and by 100% at 10 ppm exposure in all species, and there was a change in the distribution of the molecular subforms of GOT in the liver and heart. The activities of the individual subforms decreased with increasing PQ concentration or after a longer exposure. In some cases, one of the subforms was no longer present in the liver. An increased serum GOT activity, a decreased enzyme activity in different organs and the disappearance of molecular subform indicate tissue damage.

Original languageEnglish
Pages (from-to)79-83
Number of pages5
JournalFish Physiology and Biochemistry
Volume8
Issue number1
DOIs
Publication statusPublished - Jan 1 1990

Keywords

  • carp
  • heart
  • liver
  • paraquat
  • silver carp
  • tissue necrosis
  • transaminase
  • wels

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Aquatic Science

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