Effects of paraquat on peroxide metabolism enzymes and lipid peroxidation in the rat

Katalin Barabás, L. Szabó, B. Matkovics, G. Berencsi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

1. 1. Investigation has been made of how the LD50 and LD100 of PQ influence the peroxide metabolism enzymes and lipid peroxidation in organ homogenates and blood samples of the rat. 2. 2. The peroxide metabolism enzyme activities were changed in a concentration dependent manner. In general, the effect of the lower doses of PQ on the superoxide dismutase, catalase activities and lipid peroxidation are increased. The glutathione peroxidase activity was decreased. 3. 3. Higher doses of PQ enhanced all of enzyme activities and lipid peroxidation studied.

Original languageEnglish
Pages (from-to)133-137
Number of pages5
JournalGeneral Pharmacology
Volume15
Issue number2
DOIs
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Pharmacology

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