Effects of nutrition on plasma, liver and muscle amino acids in scalded rats

J. Karner, E. Roth, J. Funovics, J. Hanusch, L. R. Walzer, A. Berger, G. Meissl

Research output: Contribution to journalArticle

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Abstract

This study set out to investigate the effect of three different parenterally administered diets on the free amino acid (AA) levels in the plasma, muscle, and liver of scalded rats. Diet I consisted of AA (1.4 g/100 g weight) and a high glucose dose (6 g/100 g weight), diet II consisted of AA and a low glucose dose (1.4 g/100 g weight) and in diet III only a low glucose dose was infused. Parenteral nutrition was started on the 3rd day posttraumatically. Sampling was performed on the 7th day posttraumatically. Nitrogen balances were significantly different in all three groups, being lowest in group III. Scalded rats fed isonitrogenously, but with different amounts of glucose showed only minor changes in AA concentrations. However, scalded rats fed with a nitrogen-free diet exhibited significantly reduced total muscle and liver AA levels. These decreased AA levels were due to a drop of glycine in the muscle tissue (74%) and liver (49%). Contrary to the clinical catabolic situation in scalded and starved rats, it was not intracellular glutamine but glycine which was considerably influenced by catabolism and starvation.

Original languageEnglish
Pages (from-to)393-398
Number of pages6
JournalJournal of Parenteral and Enteral Nutrition
Volume10
Issue number4
Publication statusPublished - 1986

Fingerprint

nutrition
Amino Acids
Muscles
muscles
liver
amino acids
Diet
Liver
rats
glucose
diet
Glucose
glycine (amino acid)
Weights and Measures
Glycine
dosage
Nitrogen
parenteral feeding
nitrogen balance
muscle tissues

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Karner, J., Roth, E., Funovics, J., Hanusch, J., Walzer, L. R., Berger, A., & Meissl, G. (1986). Effects of nutrition on plasma, liver and muscle amino acids in scalded rats. Journal of Parenteral and Enteral Nutrition, 10(4), 393-398.

Effects of nutrition on plasma, liver and muscle amino acids in scalded rats. / Karner, J.; Roth, E.; Funovics, J.; Hanusch, J.; Walzer, L. R.; Berger, A.; Meissl, G.

In: Journal of Parenteral and Enteral Nutrition, Vol. 10, No. 4, 1986, p. 393-398.

Research output: Contribution to journalArticle

Karner, J, Roth, E, Funovics, J, Hanusch, J, Walzer, LR, Berger, A & Meissl, G 1986, 'Effects of nutrition on plasma, liver and muscle amino acids in scalded rats', Journal of Parenteral and Enteral Nutrition, vol. 10, no. 4, pp. 393-398.
Karner, J. ; Roth, E. ; Funovics, J. ; Hanusch, J. ; Walzer, L. R. ; Berger, A. ; Meissl, G. / Effects of nutrition on plasma, liver and muscle amino acids in scalded rats. In: Journal of Parenteral and Enteral Nutrition. 1986 ; Vol. 10, No. 4. pp. 393-398.
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