Effects of moderate aerobic exercise training on hemorheological and laboratory parameters in ischemic heart disease patients

Barbara Sandor, Alexandra Nagy, Andras Toth, Miklos Rabai, Bela Mezey, Arpad Csatho, I. Czuriga, K. Tóth, Eszter Szabados

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background and Design: In this study we set out to determine the effects of long-term physical training on hemorheological, laboratory parameters, exercise tolerability, psychological factors in cardiac patients participating in an ambulatory rehabilitation program.

Methods: Before physical training, patients were examined by echocardiography, tested on treadmill by the Bruce protocol, and blood was drawn for laboratory tests. The enrolled 79 ischemic heart disease patients joined a 24-week cardiac rehabilitation training program. Blood was drawn to measure hematocrit (Hct), plasma and whole blood viscosity (PV, WBV), red blood cell (RBC) aggregation and deformability. Hemorheological, clinical chemistry and psychological measurements were repeated 12 and 24 weeks later, and a treadmill test was performed at the end of the program.

Results: After 12 weeks Hct, PV, WBV and RBC aggregation were significantly decreased, RBC deformability exhibited a significant increase (p

Conclusions: Regular physical training improved the exercise tolerability of patients with ischemic heart disease. Previous publications have demonstrated that decreases in Hct and PV may reduce cardiovascular risk, while a decrease in RBC aggregation and an increase in deformability improve the capillary flow. Positive changes in laboratory parameters and body weight may indicate better oxidative and inflammatory circumstances and an improved metabolic state. The psychological findings point to an improvement in the quality of life.

Original languageEnglish
Article numbere110751
JournalPLoS One
Volume9
Issue number10
DOIs
Publication statusPublished - Oct 27 2014

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myocardial ischemia
Cell Aggregation
Myocardial Ischemia
exercise
Blood
erythrocytes
Erythrocytes
Hematocrit
Exercise
hematocrit
rehabilitation (people)
Psychology
Formability
Exercise equipment
blood viscosity
Agglomeration
Blood Viscosity
Clinical Chemistry
exercise test
psychosocial factors

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Effects of moderate aerobic exercise training on hemorheological and laboratory parameters in ischemic heart disease patients. / Sandor, Barbara; Nagy, Alexandra; Toth, Andras; Rabai, Miklos; Mezey, Bela; Csatho, Arpad; Czuriga, I.; Tóth, K.; Szabados, Eszter.

In: PLoS One, Vol. 9, No. 10, e110751, 27.10.2014.

Research output: Contribution to journalArticle

Sandor, Barbara ; Nagy, Alexandra ; Toth, Andras ; Rabai, Miklos ; Mezey, Bela ; Csatho, Arpad ; Czuriga, I. ; Tóth, K. ; Szabados, Eszter. / Effects of moderate aerobic exercise training on hemorheological and laboratory parameters in ischemic heart disease patients. In: PLoS One. 2014 ; Vol. 9, No. 10.
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