EFFECTS OF LOW DOSES OF IONIZING RADIATION UPON THE MICROMORPHOLOGY AND FUNCTIONAL STATE OF CELL SURFACE.

Z. Somosy, Tamara Kubasova, G. J. Koteles

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The present paper reviews the micromorphological and functional changes of plasma membranes of irradiated blood and cultured cells with special emphasis on the surface conditions: lectin binding, negative surface charges. The review is completed by our own studies on distribution of positive surface charges and the bindings of two lectins, the Concanavalin A and the wheat germ agglutinin. It was found that the decrease of negative surface charges is unconcomitant with appearance of domains exposing positive ones, particularly on the surfaces of rufflings. The distribution of Concanavalin A binding sites turned from a uniform distribution to a polarized one, especially on apical regions where it appeared in large aggregates. The polarity in localization of wheat germ agglutinin on untreated fibroblasts observed in our experiments ceased shortly after irradiation.

Original languageEnglish
Pages (from-to)1267-1278
Number of pages12
JournalScanning Microscopy
Volume1
Issue number3
Publication statusPublished - Sep 1987

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Ionizing radiation
Surface charge
ionizing radiation
Dosimetry
dosage
cells
wheat
Binding sites
Fibroblasts
Cell membranes
Blood
blood cells
Cells
Irradiation
fibroblasts
cultured cells
polarity
membranes
Experiments
irradiation

ASJC Scopus subject areas

  • Instrumentation

Cite this

EFFECTS OF LOW DOSES OF IONIZING RADIATION UPON THE MICROMORPHOLOGY AND FUNCTIONAL STATE OF CELL SURFACE. / Somosy, Z.; Kubasova, Tamara; Koteles, G. J.

In: Scanning Microscopy, Vol. 1, No. 3, 09.1987, p. 1267-1278.

Research output: Contribution to journalArticle

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