Effects of histamine on transport (Na+-K+-dependent) ATPase system (EC 3.6.1.3) prepared from human gastric mucosa

G. Mózsik, L. Nagy, F. Tárnok, T. Jávor, J. Kutas

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The transport (membrane, Na+-K+-stimulated or Na+-K+-dependent) ATPase (EC 3.6.1.3) was prepared from fundic gastric mucosa of operated patients and the histamine effect was studied on its activity. It has been observed that histamine significantly stimulated the Mg2+-dependent part, on the one hand, and inhibited the total and Na+-K+-dependent ATPase activity from membrane fractions of human gastric mucosa, on the other hand. The interrelationship between the transport ATPase system and the adenyl cyclase system, at the level of the cell membrane, is reviewed.

Original languageEnglish
Pages (from-to)193-200
Number of pages8
JournalPharmacology
Volume12
Issue number4-5
DOIs
Publication statusPublished - 1974

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Gastric Mucosa
Histamine
Adenosine Triphosphatases
Histamine Agents
Membranes
Adenylyl Cyclases
Cell Membrane

Keywords

  • Adenyl cyclase system
  • Cell membrane
  • Feed-back mechanisms
  • HCl secretion
  • Histamine effect
  • Human gastric mucosa
  • Transport ATPase system

ASJC Scopus subject areas

  • Pharmacology

Cite this

Effects of histamine on transport (Na+-K+-dependent) ATPase system (EC 3.6.1.3) prepared from human gastric mucosa. / Mózsik, G.; Nagy, L.; Tárnok, F.; Jávor, T.; Kutas, J.

In: Pharmacology, Vol. 12, No. 4-5, 1974, p. 193-200.

Research output: Contribution to journalArticle

Mózsik, G. ; Nagy, L. ; Tárnok, F. ; Jávor, T. ; Kutas, J. / Effects of histamine on transport (Na+-K+-dependent) ATPase system (EC 3.6.1.3) prepared from human gastric mucosa. In: Pharmacology. 1974 ; Vol. 12, No. 4-5. pp. 193-200.
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AU - Jávor, T.

AU - Kutas, J.

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