Effects of glutaurine treatment on electroshock-induced amnesia. Antiamnesic action of glutaurine

M. Balázs, G. Telegdy

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The effects of oral glutaurine (gamma-L-glutamyl-taurine, LitoralonR Chinoin, Budapest) treatment on electroconvulsive shock-induced amnesia were studied. Oral treatment with glutaurine in a dose of 1-20 μg was ineffective on electroshock-induced amnesia if the treatment was applied before the electroconvulsive shock. Fifty μg given in the same experimental paradigm could attenuate the amnesia considerably. When the treatment with glutaurine was applied immediately after the electroconvulsive shock, even 1 and 10 μg doses were effective in attenuating the amnesia in both the 24h and 48h retestings. However when glutaurine was given one hour before the 24h and 48h retestings, it proved to be ineffective. The data indicate that glutaurine is able to prevent electroconvulsive shock-induced amnesia by counteracting the effect of the electroconvulsive shock on the memory consolidation phase, but it is less effective on learning or it is ineffective on retrieval processes.

Original languageEnglish
Pages (from-to)55-58
Number of pages4
JournalNeuropeptides
Volume12
Issue number2
DOIs
Publication statusPublished - 1988

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Electroshock
Amnesia
Consolidation
glutaurine
Learning
Data storage equipment

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Clinical Neurology
  • Neuroscience(all)
  • Cellular and Molecular Neuroscience

Cite this

Effects of glutaurine treatment on electroshock-induced amnesia. Antiamnesic action of glutaurine. / Balázs, M.; Telegdy, G.

In: Neuropeptides, Vol. 12, No. 2, 1988, p. 55-58.

Research output: Contribution to journalArticle

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