A doxycyclin-kezelés hatása terhességben

Translated title of the contribution: Effects of doxycydine treatment upon pregnancy

Kazy Zoltán, E. Puhó, E. Czeizel

Research output: Contribution to journalArticle

Abstract

Objective: To study the effect of oral doxycycline treatment during pregnancy for pregnancy complications and delivery outcomes particularly preterm delivery/birth. Methods: The newborn infants without congenital abnormalities in the data set of the population-based Hungarian Case-Control Surveillance of Congenital Abnormalities, 1980-1997 were evaluated. Results: Of 38.151 newborn infants, 78 had mothers with doxycycline treatment during pregnancy. Their mean gestational age was 39.8±2.0 weeks compared with the figure of 39.4±2.0 weeks in untreated women. The proportion of preterm birth was 3.8 % versus 9.2 % in the treated and untreated groups. The possible preterm preventive effect of doxycycline was found after the treatment in the first and second trimester of pregnancy. Conclusions: Treatment with doxycycline during the first and second trimester of pregnancy can reduce the preterm birth associated with acute infectious maternal diseases of the genital organs.

Original languageHungarian
Pages (from-to)107-112
Number of pages6
JournalMagyar Noorvosok Lapja
Volume71
Issue number3
Publication statusPublished - 2008

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Doxycycline
Premature Birth
Pregnancy
Second Pregnancy Trimester
First Pregnancy Trimester
Mothers
Newborn Infant
Genitalia
Pregnancy Complications
Therapeutics
Gestational Age
Communicable Diseases
Population

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

A doxycyclin-kezelés hatása terhességben. / Zoltán, Kazy; Puhó, E.; Czeizel, E.

In: Magyar Noorvosok Lapja, Vol. 71, No. 3, 2008, p. 107-112.

Research output: Contribution to journalArticle

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