Lymphocytes and macrophages which infiltrate the host-tumor interface in choriocarcinoma, on activation by paternal antigens, produces soluble paracrine factors known as cytokines, which regulate cellular growth. The authors demonstrate that interleukin-1α, interleukin-1β and tumor necrosis factor - as human recombinant cytokines, significantly increase the epidermal growth factor receptor expression on JEG-3 choriocarcinoma cells and support the concept that cytokines are involved in choriocarcinoma cell growth through epidermal growth factor receptors.
|Number of pages||4|
|Journal||Magyar Noorvosok Lapja|
|Publication status||Published - Dec 1 1992|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology