Effects of chicory on pancreas status of rats in experimental dislipidemia

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16 Citations (Scopus)

Abstract

The well known medicinal plant, Cichorium intybus L. (Asteraceae) contains dietary oligofructose compounds which have beneficial effect on carbohydrate and lipid metabolism, other compounds e.g. polyphenol type derivatives could be responsible for the antioxidant properties reported in several studies before. Male Fischer rats were kept on normal and lipid rich diet supplemented with chicory extract in this study. Our aim was to investigate the influence of this supplementation on pancreas status of rats, especially in dislipidemia. Polyphenols, flavonoids and caffeic acid derivatives were measured in chicory extract by spectrophotometric and chromatographic methods. Antioxidant property of the plant extract was determined in vitro and the biological activity of antioxidant compounds of chicory was investigated in vivo by a luminometric technique.The effects of bioactive molecules of chicory extract influenced the lipid metabolism and the redox balance of pancreatic tissue of rats in experimental dislipidemia.

Original languageEnglish
Pages (from-to)143-146
Number of pages4
JournalActa Biologica Szegediensis
Volume47
Issue number1-4
Publication statusPublished - 2003

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Chicory
chicory
pancreas
Rats
Pancreas
Antioxidants
Polyphenols
rats
antioxidants
lipid metabolism
Derivatives
polyphenols
extracts
Lipid Metabolism
chemical derivatives
Plant Extracts
Nutrition
Bioactivity
Flavonoids
Cichorium intybus

Keywords

  • Antioxidant status
  • Cichorium intybus
  • Hyperlipidemy
  • Pancreas

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Cell Biology
  • Neuroscience(all)
  • Applied Microbiology and Biotechnology

Cite this

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abstract = "The well known medicinal plant, Cichorium intybus L. (Asteraceae) contains dietary oligofructose compounds which have beneficial effect on carbohydrate and lipid metabolism, other compounds e.g. polyphenol type derivatives could be responsible for the antioxidant properties reported in several studies before. Male Fischer rats were kept on normal and lipid rich diet supplemented with chicory extract in this study. Our aim was to investigate the influence of this supplementation on pancreas status of rats, especially in dislipidemia. Polyphenols, flavonoids and caffeic acid derivatives were measured in chicory extract by spectrophotometric and chromatographic methods. Antioxidant property of the plant extract was determined in vitro and the biological activity of antioxidant compounds of chicory was investigated in vivo by a luminometric technique.The effects of bioactive molecules of chicory extract influenced the lipid metabolism and the redox balance of pancreatic tissue of rats in experimental dislipidemia.",
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T1 - Effects of chicory on pancreas status of rats in experimental dislipidemia

AU - Kocsis, I.

AU - Hagymási, K.

AU - Kéry, A.

AU - Szőke, E.

AU - Blázovics, A.

PY - 2003

Y1 - 2003

N2 - The well known medicinal plant, Cichorium intybus L. (Asteraceae) contains dietary oligofructose compounds which have beneficial effect on carbohydrate and lipid metabolism, other compounds e.g. polyphenol type derivatives could be responsible for the antioxidant properties reported in several studies before. Male Fischer rats were kept on normal and lipid rich diet supplemented with chicory extract in this study. Our aim was to investigate the influence of this supplementation on pancreas status of rats, especially in dislipidemia. Polyphenols, flavonoids and caffeic acid derivatives were measured in chicory extract by spectrophotometric and chromatographic methods. Antioxidant property of the plant extract was determined in vitro and the biological activity of antioxidant compounds of chicory was investigated in vivo by a luminometric technique.The effects of bioactive molecules of chicory extract influenced the lipid metabolism and the redox balance of pancreatic tissue of rats in experimental dislipidemia.

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KW - Hyperlipidemy

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