EFFECTS OF CHANGE IN BODY POSTURE ON PLASMA AND SERUM ELECTROLYTES IN NORMAL SUBJECTS AND IN PRIMARY ALDOSTERONISM

S. SONKODI, M. G. NICHOLLS, A. M.M. CUMMING, J. I.S. ROBERTSON

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We observed that change in body posture from the supine to the erect position in normal volunteers was associated with a rise in circulating potassium and a fall in sodium concentrations, irrespective of whether the electrolytes were measured in serum or plasma, or whether head‐up tilt or ambulation was used. In patients with primary aldosteronism, the fall in serum sodium and rise in serum potassium with ambulation tended to obscure the characteristic electrolyte abnormalities of that syndrome. These changes in potassium and sodium could contribute to the rise in aldosterone secretion on orthostasis. The body posture of patients should be considered in the interpretation of plasma and serum electrolyte levels.

Original languageEnglish
Pages (from-to)613-620
Number of pages8
JournalClinical Endocrinology
Volume14
Issue number6
DOIs
Publication statusPublished - Jun 1981

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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