Effects of bursectomy and thymectomy on the development of resistance to Cryptosporidium baileyi in chickens

T. Sréter, I. Varga, L. Békési

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Comparisons were made between the course of infection with Cryptosporidium baileyi in normal chickens and in chickens with functional deficiencies in either B-lymphocytes (bursectomized) or T-lymphocytes (thymectomized). Bursectomy did not influence the acquired immune response to C. baileyi infection as measured by the oocyst excretion. However, the total oocyst output of bursectomized birds was less than a quarter of that of the controls due to the reduced site for multiplication of the parasite. The total oocyst output of thymectomized chickens was more than 2 times higher and the patency was 2 times longer as compared with control animals. Moreover, thymectomized birds failed to acquire resistance to the challenge infection. These findings attest to the primary role of cell-mediated immunity in the expression of resistance to C. baileyi as opposed to the antibody-mediated mechanisms.

Original languageEnglish
Pages (from-to)174-177
Number of pages4
JournalParasitology Research
Volume82
Issue number2
DOIs
Publication statusPublished - 1996

Fingerprint

Cryptosporidium baileyi
Cryptosporidium
Thymectomy
Oocysts
oocysts
Chickens
chickens
Birds
Infection
infection
birds
Cellular Immunity
cell-mediated immunity
B-lymphocytes
Parasites
B-Lymphocytes
excretion
T-lymphocytes
immune response
T-Lymphocytes

ASJC Scopus subject areas

  • Parasitology

Cite this

Effects of bursectomy and thymectomy on the development of resistance to Cryptosporidium baileyi in chickens. / Sréter, T.; Varga, I.; Békési, L.

In: Parasitology Research, Vol. 82, No. 2, 1996, p. 174-177.

Research output: Contribution to journalArticle

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