Effects of black radish root (Raphanus sativus L. var niger) on the colon mucosa in rats fed a fat rich diet

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Abstract

The effect of black radish root (Raphanus sativus L. var niger) was studied on the structure and redox state of the colon mucosa in fat-rich diet fed rats. The epithelial lining disrupted, the number of enterocytes and the goblet cells reduced and inflammatory cells were observed in rats fed with a fat-rich diet. After treatment with granules from black radish root all of the histopathological changes and parameters of the redox state caused by the fat-rich diet were improved. The structure of the epithelial cells was similar to the controls, the number of goblet cells increased and no inflammation was observed.

Original languageEnglish
Pages (from-to)677-679
Number of pages3
JournalPhytotherapy Research
Volume16
Issue number7
DOIs
Publication statusPublished - Nov 2002

Fingerprint

Raphanus
Niger
Nutrition
Rats
Colon
Mucous Membrane
Goblet Cells
Fats
Diet
Oxidation-Reduction
Enterocytes
Linings
Epithelial Cells
Inflammation

Keywords

  • Black radish root
  • Colon mucosa
  • Free radicals

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

Cite this

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abstract = "The effect of black radish root (Raphanus sativus L. var niger) was studied on the structure and redox state of the colon mucosa in fat-rich diet fed rats. The epithelial lining disrupted, the number of enterocytes and the goblet cells reduced and inflammatory cells were observed in rats fed with a fat-rich diet. After treatment with granules from black radish root all of the histopathological changes and parameters of the redox state caused by the fat-rich diet were improved. The structure of the epithelial cells was similar to the controls, the number of goblet cells increased and no inflammation was observed.",
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AU - Sipos, P.

AU - Hagymási, K.

AU - Lugasi, A.

AU - Fehér, E.

AU - Blázovics, A.

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N2 - The effect of black radish root (Raphanus sativus L. var niger) was studied on the structure and redox state of the colon mucosa in fat-rich diet fed rats. The epithelial lining disrupted, the number of enterocytes and the goblet cells reduced and inflammatory cells were observed in rats fed with a fat-rich diet. After treatment with granules from black radish root all of the histopathological changes and parameters of the redox state caused by the fat-rich diet were improved. The structure of the epithelial cells was similar to the controls, the number of goblet cells increased and no inflammation was observed.

AB - The effect of black radish root (Raphanus sativus L. var niger) was studied on the structure and redox state of the colon mucosa in fat-rich diet fed rats. The epithelial lining disrupted, the number of enterocytes and the goblet cells reduced and inflammatory cells were observed in rats fed with a fat-rich diet. After treatment with granules from black radish root all of the histopathological changes and parameters of the redox state caused by the fat-rich diet were improved. The structure of the epithelial cells was similar to the controls, the number of goblet cells increased and no inflammation was observed.

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KW - Colon mucosa

KW - Free radicals

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