Effects of artificial sweeteners on body weight, food and drink intake

Éiva Polyák, K. Gombos, B. Hajnal, K. Bonyár-Müller, Sz Szabó, A. Gubicskó-Kisbenedek, K. Marton, I. Ember

Research output: Contribution to journalArticle

17 Citations (Scopus)


Artificial sweeteners are widely used all over the world. They may assist in weight management, prevention of dental caries, control of blood glucose of diabetics, and also can be used to replace sugar in foods. In the animal experimentation mice were given oral doses of water solutions of table top artificial sweeteners (saccharin, cyclamate based, acesulfame-K based, and aspartame) the amount of maximum Acceptable Daily Intake (ADI) ad libitum. The controls received only tap water with the same drinking conditions as the treated groups. The mice were fed chow ad libitum.We measured food intake and body weight once a week, water and solutions of artificial sweeteners intake twice a week. The data were analysed by statistical methods (T-probe, regression analysis).Consumption of sweeteners resulted in significantly increased body weight; however, the food intake did not change.These results question the effect of non-caloric artificial sweeteners on weight-maintenance or body weight decrease.

Original languageEnglish
Pages (from-to)401-407
Number of pages7
JournalActa physiologica Hungarica
Issue number4
Publication statusPublished - Dec 1 2010



  • artificial sweeteners
  • body weight changes
  • fluid intake
  • food intake

ASJC Scopus subject areas

  • Physiology (medical)

Cite this

Polyák, É., Gombos, K., Hajnal, B., Bonyár-Müller, K., Szabó, S., Gubicskó-Kisbenedek, A., Marton, K., & Ember, I. (2010). Effects of artificial sweeteners on body weight, food and drink intake. Acta physiologica Hungarica, 97(4), 401-407. https://doi.org/10.1556/APhysiol.97.2010.4.9