Effects of alkali metal ions on some virulence traits of Candida albicans

P. Hermann, K. Forgács, E. Gál, B. Lenkey, G. Nagy, F. Rozgonyi

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The effects of the alkali metal ions (Li+, Na+ and K+) on the growth and on certain virulence factors (adhesion, cell-surface hydrophobicity and germinating ability) of Candida albicans were determined. High concentrations of these ions displayed an inhibitory effect on the growth of the Candida cells; preincubation in their presence showed a negative effect on all virulence factors studied. The changes induced during the preincubation remained there even when high concentration of the ions was removed from the cell suspension. In contrast, a considerable growth was found at high Na+ and K+ concentrations. Although alkali metal ions significantly decreased certain virulence traits of the fungus they did not totally inhibit adhesion and germ-tube formation. This suggests that C. albicans may represent a health hazard even at a high salt concentration.

Original languageEnglish
Pages (from-to)173-176
Number of pages4
JournalFolia Microbiologica
Volume48
Issue number2
DOIs
Publication statusPublished - Mar 2003

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Alkali Metals
Candida albicans
Virulence
Ions
Virulence Factors
Growth
Hydrophobic and Hydrophilic Interactions
Candida
Cell Adhesion
Suspensions
Fungi
Salts
Health

ASJC Scopus subject areas

  • Microbiology

Cite this

Effects of alkali metal ions on some virulence traits of Candida albicans. / Hermann, P.; Forgács, K.; Gál, E.; Lenkey, B.; Nagy, G.; Rozgonyi, F.

In: Folia Microbiologica, Vol. 48, No. 2, 03.2003, p. 173-176.

Research output: Contribution to journalArticle

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