Effectiveness of garlic on the radical activity in radical generating systems

B. Torok, J. Belágyi, B. Rietz, R. Jacob

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

The radical scavenging capacity of garlic (allium sativum) has been investigated in vitro in radical generating systems by electron paramagnetic resonance (EPR) and low-level chemiluminescence measurements. Garlic (both the homogenate of 10% in physiological saline solution and its supernatant) was able to reduce the radicals generated by the Fenton reaction and trapped by phenyl-butyl-nitron for EPR measurements. Also radicals present in cigarette smoke could be reduced by garlic as judged from chemiluminescence in the presence of tert.-butyl-hydroperoxide. According to the in vitro measurements garlic contains substances which have significant radical scavenging capacity.

Original languageEnglish
Pages (from-to)608-611
Number of pages4
JournalArzneimittel-Forschung
Volume44
Issue number5
Publication statusPublished - 1994

Fingerprint

Garlic
Chemiluminescence
Scavenging
Paramagnetic resonance
Electron Spin Resonance Spectroscopy
Sodium Chloride
Smoke
Tobacco Products
Hydrogen Peroxide
Luminescent Measurements
Luminescence

Keywords

  • allium sativum
  • garlic, radical scavenging

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Chemistry(all)
  • Pharmacology

Cite this

Effectiveness of garlic on the radical activity in radical generating systems. / Torok, B.; Belágyi, J.; Rietz, B.; Jacob, R.

In: Arzneimittel-Forschung, Vol. 44, No. 5, 1994, p. 608-611.

Research output: Contribution to journalArticle

Torok, B. ; Belágyi, J. ; Rietz, B. ; Jacob, R. / Effectiveness of garlic on the radical activity in radical generating systems. In: Arzneimittel-Forschung. 1994 ; Vol. 44, No. 5. pp. 608-611.
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