Effect of vitamin E supplementation on immunity against newcastle disease virus in T-2 toxin challenged chickens

Mária Kovács-Weber, J. Fodor, K. Balogh, L. Wágner, M. Erdélyi, Miklós Mézes

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5 Citations (Scopus)


The effect of T-2 toxin contaminated feed (2.35 mg·kg-1) and/or vitamin E supplementation in drinking water (10.5 mg/ animal·day-1) for 14 days on the haemagglutination inhibition titres against Newcastle disease virus was investigated in repeatedly vaccinated (on 23 days of age) broiler chicken. The animals were divided into four groups: (1) control; (2) treated with vitamin E; (3) fed a T-2 toxin contaminated feed; (4) fed a T-2 toxin contaminated diet and treated with vitamin E. Blood samples were taken on days 7 and 14 of the experiment for determination of sera titres and vitamin E content, liver samples were also taken on the same days for vitamin E determination. It was found that haemagglutination titres increased in comparison to the controls as an effect of vitamin E supply and also a low dose T-2 toxin challenge. The combination of both treatments showed some synergistic effect. The utilization of vitamin E decreased by the feeding of T-2 toxin contaminated diet, particularly in the liver.

Original languageEnglish
Pages (from-to)45-49
Number of pages5
JournalActa Veterinaria Brno
Issue number1
Publication statusPublished - Mar 1 2008



  • Chicken
  • Haemagglutination inhibition
  • Newcastle disease
  • T-2 toxin
  • Vitamin E

ASJC Scopus subject areas

  • veterinary(all)

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