Effect of vitamin E on the immunoreactivity of spleen cells in hyperlipidaemic rats

R. Gonzalez-Cabello, A. Blázovics, M. E. Horvath, G. Müzes, P. Gergely, J. Fehér

Research output: Contribution to journalArticle

Abstract

Atherogenic (lipid-rich) diet suppressed mitogen-induced lymphocyte blastogenic responses in rats. Supplementation with vitamin E completely abolished the suppressive effect of the diet. The atherogenic diet also decreased the tumour necrosis factor alpha (TNF-α) activity produced by spleen macrophages, however, vitamin E supplementation failed to abolish this effect. Diet or supplementation had no measurable action on interleukin-1 (IL-1) production of macrophages.

Original languageEnglish
Pages (from-to)101-108
Number of pages8
JournalActa Medica Hungarica
Volume49
Issue number1-2
Publication statusPublished - 1992

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Vitamin E
Spleen
Diet
Macrophages
Atherogenic Diet
Interleukin-1
Mitogens
Tumor Necrosis Factor-alpha
Lymphocytes
Lipids

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Effect of vitamin E on the immunoreactivity of spleen cells in hyperlipidaemic rats. / Gonzalez-Cabello, R.; Blázovics, A.; Horvath, M. E.; Müzes, G.; Gergely, P.; Fehér, J.

In: Acta Medica Hungarica, Vol. 49, No. 1-2, 1992, p. 101-108.

Research output: Contribution to journalArticle

Gonzalez-Cabello, R. ; Blázovics, A. ; Horvath, M. E. ; Müzes, G. ; Gergely, P. ; Fehér, J. / Effect of vitamin E on the immunoreactivity of spleen cells in hyperlipidaemic rats. In: Acta Medica Hungarica. 1992 ; Vol. 49, No. 1-2. pp. 101-108.
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