Vergleichende Untersuchungen des Renin-Angiotensin-Systems nach Urethan- und Penthobarbitalnarkose

Translated title of the contribution: Effect of urethane and penthobarbital on the behaviour of the renin-angiotensin-system in rat

S. Sonkodi, J. Náfrádi

Research output: Contribution to journalArticle

5 Citations (Scopus)


The behaviour of the renin-angiotensin-system was investigated after urethane and penthobarbital anaesthesia in rats. The recent results support the early observation that urethane increases the plasma-reninactivity and the haematocrit. It was further shown that urethane in the customary anaesthetic dose causes hypoproteinaemia and a decrease in the pressor response to angiotensin and in renin substrate concentration. Based on these results, its use as an anaesthetic in experiments connected with the renin-angiotensin-system does not appear to be appropriate.

Original languageGerman
Pages (from-to)301-306
Number of pages6
JournalResearch In Experimental Medicine
Issue number3
Publication statusPublished - Oct 1 1979



  • Angiotensin pressor response
  • Blood pressure
  • Permeability of blood-vessels
  • Renin-angiotensin-system
  • Urethane anaesthesia

ASJC Scopus subject areas

  • Medicine(all)

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