Effect of unilateral or bilateral thyroidectomy on TRH content of hypothalamus halves

I. Gerendai, A. Nemeskéri, A. Faivre-Bauman, D. Grouselle, A. Tixier-Vidal

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The effect of uni-or bilateral thyroidectomy on the thyrotropin-releasing hormone (TRH) content of the mediobasal hypothalamus (MBH) of the two sides was studied in male rats. Both right- and left-side hemithyroidectomy resulted in a significantly increased TRH content in both halves of the MBH. In addition, the total TRH content rise of the MBH was higher after unilateral than after bilateral thyroidectomy. The mechanism of action of uni-or bilateral thyroidectomy on the hypothalamic TRH content is discussed.

Original languageEnglish
Pages (from-to)321-323
Number of pages3
JournalJournal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology
Volume8
Issue number4
DOIs
Publication statusPublished - Aug 1985

Keywords

  • TRH
  • hemithyroidectomy
  • hypothalamus
  • rat

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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