Effect of type of early infant feeding on fatty acid composition of plasma lipid classes in full-term infants during the second 6 months of life

Tamás Decsi, Barbara Kelemen, Hajnalka Minda, István Burus, Gerhard Kohn

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Background: Previously, the authors found significantly higher arachidonic and docosahexaenoic acid values in plasma lipids in 2-month-old full-term infants fed human milk than in those receiving formula. This is the report of data obtained in full-term infants during the second half of the first year of life. Methods: Healthy, full-term infants fed human milk (n = 12) or formula without preformed long-chain polyunsaturated fatty acids (n = 12) were investigated. Fatty acid composition of plasma lipid classes was determined by high-resolution capillary gas-liquid chromatography. Results: Linoleic acid acid values in plasma phospholipids (18.5 [3.94] vs. 20.79 [4.34]) and γ-linolenic acid values in plasma cholesteryl esters (0.17 [0.09] vs. 0.27 [0.20]) and triacylglycerols (0.27 [0.18] vs. 0.46 [0.27]) were significantly (P <0.05) lower in breast-fed infants than in those receiving formula. Data are percentage weight by weight shown as median (range from 1 st to 3rd quartile) for breast-fed vs. formula fed infants, respectively. In contrast, arachidonic acid values in plasma phospholipids (10.05 [2.90] vs. 7.03 [1.87]; P <0.01), cholesteryl esters (7.54 [3.58] vs. 4.09 [1.81]; P <0.05), and triacylglycerols (1.28 [0.84] vs. 0.80 [0.39]; P <0.05), as well as docosahexaenoic acid values in plasma phospholipids (1.92 [0.36] vs. 1.02 [0.31]; P <0.001), cholesteryl esters (0.39 [0.13] vs. 0.15 [0.13]; P <0.001), and triacylglycerols (0.17 [0.17] vs. 0.09 [0.04]; P <0.01) were significantly higher in infants fed human milk than in those receiving formula. Conclusion: Healthy, full-term infants fed formula without preformed dietary long-chain polyunsaturated fatty acids are unable to match the arachidonic and docosahexaenoic acid status of breast-fed infants even during the second half of the first year of life. (C) 2000 Lippincott Williams and Wilkins, Inc.

Original languageEnglish
Pages (from-to)547-551
Number of pages5
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume30
Issue number5
DOIs
Publication statusPublished - May 2000

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infant feeding
blood lipids
acid value
Fatty Acids
fatty acid composition
Lipids
cholesteryl esters
Cholesterol Esters
Human Milk
breast milk
docosahexaenoic acid
arachidonic acid
Arachidonic Acid
breasts
Phospholipids
phospholipids
Infant Formula
Triglycerides
Breast
long chain polyunsaturated fatty acids

Keywords

  • Arachidonic acid
  • Docosahexaenoic acid
  • Essential fatty acids
  • Full-term infant
  • Long-chain polyunsaturated fatty acids
  • Plasma lipid classes

ASJC Scopus subject areas

  • Gastroenterology
  • Histology
  • Medicine (miscellaneous)
  • Food Science
  • Pediatrics, Perinatology, and Child Health

Cite this

Effect of type of early infant feeding on fatty acid composition of plasma lipid classes in full-term infants during the second 6 months of life. / Decsi, Tamás; Kelemen, Barbara; Minda, Hajnalka; Burus, István; Kohn, Gerhard.

In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 30, No. 5, 05.2000, p. 547-551.

Research output: Contribution to journalArticle

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title = "Effect of type of early infant feeding on fatty acid composition of plasma lipid classes in full-term infants during the second 6 months of life",
abstract = "Background: Previously, the authors found significantly higher arachidonic and docosahexaenoic acid values in plasma lipids in 2-month-old full-term infants fed human milk than in those receiving formula. This is the report of data obtained in full-term infants during the second half of the first year of life. Methods: Healthy, full-term infants fed human milk (n = 12) or formula without preformed long-chain polyunsaturated fatty acids (n = 12) were investigated. Fatty acid composition of plasma lipid classes was determined by high-resolution capillary gas-liquid chromatography. Results: Linoleic acid acid values in plasma phospholipids (18.5 [3.94] vs. 20.79 [4.34]) and γ-linolenic acid values in plasma cholesteryl esters (0.17 [0.09] vs. 0.27 [0.20]) and triacylglycerols (0.27 [0.18] vs. 0.46 [0.27]) were significantly (P <0.05) lower in breast-fed infants than in those receiving formula. Data are percentage weight by weight shown as median (range from 1 st to 3rd quartile) for breast-fed vs. formula fed infants, respectively. In contrast, arachidonic acid values in plasma phospholipids (10.05 [2.90] vs. 7.03 [1.87]; P <0.01), cholesteryl esters (7.54 [3.58] vs. 4.09 [1.81]; P <0.05), and triacylglycerols (1.28 [0.84] vs. 0.80 [0.39]; P <0.05), as well as docosahexaenoic acid values in plasma phospholipids (1.92 [0.36] vs. 1.02 [0.31]; P <0.001), cholesteryl esters (0.39 [0.13] vs. 0.15 [0.13]; P <0.001), and triacylglycerols (0.17 [0.17] vs. 0.09 [0.04]; P <0.01) were significantly higher in infants fed human milk than in those receiving formula. Conclusion: Healthy, full-term infants fed formula without preformed dietary long-chain polyunsaturated fatty acids are unable to match the arachidonic and docosahexaenoic acid status of breast-fed infants even during the second half of the first year of life. (C) 2000 Lippincott Williams and Wilkins, Inc.",
keywords = "Arachidonic acid, Docosahexaenoic acid, Essential fatty acids, Full-term infant, Long-chain polyunsaturated fatty acids, Plasma lipid classes",
author = "Tam{\'a}s Decsi and Barbara Kelemen and Hajnalka Minda and Istv{\'a}n Burus and Gerhard Kohn",
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T1 - Effect of type of early infant feeding on fatty acid composition of plasma lipid classes in full-term infants during the second 6 months of life

AU - Decsi, Tamás

AU - Kelemen, Barbara

AU - Minda, Hajnalka

AU - Burus, István

AU - Kohn, Gerhard

PY - 2000/5

Y1 - 2000/5

N2 - Background: Previously, the authors found significantly higher arachidonic and docosahexaenoic acid values in plasma lipids in 2-month-old full-term infants fed human milk than in those receiving formula. This is the report of data obtained in full-term infants during the second half of the first year of life. Methods: Healthy, full-term infants fed human milk (n = 12) or formula without preformed long-chain polyunsaturated fatty acids (n = 12) were investigated. Fatty acid composition of plasma lipid classes was determined by high-resolution capillary gas-liquid chromatography. Results: Linoleic acid acid values in plasma phospholipids (18.5 [3.94] vs. 20.79 [4.34]) and γ-linolenic acid values in plasma cholesteryl esters (0.17 [0.09] vs. 0.27 [0.20]) and triacylglycerols (0.27 [0.18] vs. 0.46 [0.27]) were significantly (P <0.05) lower in breast-fed infants than in those receiving formula. Data are percentage weight by weight shown as median (range from 1 st to 3rd quartile) for breast-fed vs. formula fed infants, respectively. In contrast, arachidonic acid values in plasma phospholipids (10.05 [2.90] vs. 7.03 [1.87]; P <0.01), cholesteryl esters (7.54 [3.58] vs. 4.09 [1.81]; P <0.05), and triacylglycerols (1.28 [0.84] vs. 0.80 [0.39]; P <0.05), as well as docosahexaenoic acid values in plasma phospholipids (1.92 [0.36] vs. 1.02 [0.31]; P <0.001), cholesteryl esters (0.39 [0.13] vs. 0.15 [0.13]; P <0.001), and triacylglycerols (0.17 [0.17] vs. 0.09 [0.04]; P <0.01) were significantly higher in infants fed human milk than in those receiving formula. Conclusion: Healthy, full-term infants fed formula without preformed dietary long-chain polyunsaturated fatty acids are unable to match the arachidonic and docosahexaenoic acid status of breast-fed infants even during the second half of the first year of life. (C) 2000 Lippincott Williams and Wilkins, Inc.

AB - Background: Previously, the authors found significantly higher arachidonic and docosahexaenoic acid values in plasma lipids in 2-month-old full-term infants fed human milk than in those receiving formula. This is the report of data obtained in full-term infants during the second half of the first year of life. Methods: Healthy, full-term infants fed human milk (n = 12) or formula without preformed long-chain polyunsaturated fatty acids (n = 12) were investigated. Fatty acid composition of plasma lipid classes was determined by high-resolution capillary gas-liquid chromatography. Results: Linoleic acid acid values in plasma phospholipids (18.5 [3.94] vs. 20.79 [4.34]) and γ-linolenic acid values in plasma cholesteryl esters (0.17 [0.09] vs. 0.27 [0.20]) and triacylglycerols (0.27 [0.18] vs. 0.46 [0.27]) were significantly (P <0.05) lower in breast-fed infants than in those receiving formula. Data are percentage weight by weight shown as median (range from 1 st to 3rd quartile) for breast-fed vs. formula fed infants, respectively. In contrast, arachidonic acid values in plasma phospholipids (10.05 [2.90] vs. 7.03 [1.87]; P <0.01), cholesteryl esters (7.54 [3.58] vs. 4.09 [1.81]; P <0.05), and triacylglycerols (1.28 [0.84] vs. 0.80 [0.39]; P <0.05), as well as docosahexaenoic acid values in plasma phospholipids (1.92 [0.36] vs. 1.02 [0.31]; P <0.001), cholesteryl esters (0.39 [0.13] vs. 0.15 [0.13]; P <0.001), and triacylglycerols (0.17 [0.17] vs. 0.09 [0.04]; P <0.01) were significantly higher in infants fed human milk than in those receiving formula. Conclusion: Healthy, full-term infants fed formula without preformed dietary long-chain polyunsaturated fatty acids are unable to match the arachidonic and docosahexaenoic acid status of breast-fed infants even during the second half of the first year of life. (C) 2000 Lippincott Williams and Wilkins, Inc.

KW - Arachidonic acid

KW - Docosahexaenoic acid

KW - Essential fatty acids

KW - Full-term infant

KW - Long-chain polyunsaturated fatty acids

KW - Plasma lipid classes

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JO - Journal of Pediatric Gastroenterology and Nutrition

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