Effect of tonsillectomy and its timing on renal outcomes in Caucasian IgA nephropathy patients

Tibor Kovács, Tibor Vas, Csaba P. Kövesdy, Péter Degrell, Györgyi Nagy, Zsuzsanna Rékási, I. Wittmann, J. Nagy

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Results: One-hundred and sixty-six patients did not undergo tonsillectomy (Group I, follow-up 130 ± 101 months) and 98 patients underwent tonsillectomy (Group II, follow-up 170 ± 124 months). The mean renal survival time was significantly longer for both end-points between those patients who underwent tonsillectomy (Group II) versus patients without tonsillectomy (Group I) (p 

Conclusion: Tonsillectomy may delay the progression of IgA nephropathy mainly in IgA nephropathy patients with macrohaematuria. Prospective investigation of the protective role of tonsillectomy in Caucasian patients is needed.

Purpose: The role of tonsillectomy in the treatment of IgA nephropathy in Caucasian patients is controversial.

Methods: A retrospective cohort study was conducted in 264 patients with biopsy-proven primary IgA nephropathy to examine the association between tonsillectomy and long-term renal survival, defined as the incidence of estimated glomerular filtration rates (eGFRs) of ≤30 ml/min/1.73 m2 or end-stage renal disease (the composite of initiation of dialysis treatment or renal transplantation). The association of tonsillectomy with renal end-points was examined using the Kaplan–Meier method and Cox models.

Original languageEnglish
Pages (from-to)2175-2182
Number of pages8
JournalInternational Urology and Nephrology
Volume46
Issue number11
DOIs
Publication statusPublished - Oct 25 2014

Fingerprint

Tonsillectomy
Immunoglobulin A
Kidney
Glomerular Filtration Rate
Proportional Hazards Models
Kidney Transplantation
Chronic Kidney Failure
Dialysis
Cohort Studies
Survival Rate
Retrospective Studies
Biopsy
Incidence

Keywords

  • IgA nephropathy
  • Progression of IgA nephropathy
  • Tonsillectomy

ASJC Scopus subject areas

  • Nephrology
  • Urology
  • Medicine(all)

Cite this

Effect of tonsillectomy and its timing on renal outcomes in Caucasian IgA nephropathy patients. / Kovács, Tibor; Vas, Tibor; Kövesdy, Csaba P.; Degrell, Péter; Nagy, Györgyi; Rékási, Zsuzsanna; Wittmann, I.; Nagy, J.

In: International Urology and Nephrology, Vol. 46, No. 11, 25.10.2014, p. 2175-2182.

Research output: Contribution to journalArticle

Kovács, Tibor ; Vas, Tibor ; Kövesdy, Csaba P. ; Degrell, Péter ; Nagy, Györgyi ; Rékási, Zsuzsanna ; Wittmann, I. ; Nagy, J. / Effect of tonsillectomy and its timing on renal outcomes in Caucasian IgA nephropathy patients. In: International Urology and Nephrology. 2014 ; Vol. 46, No. 11. pp. 2175-2182.
@article{cafe42f7d779451fa9510006181b02e6,
title = "Effect of tonsillectomy and its timing on renal outcomes in Caucasian IgA nephropathy patients",
abstract = "Results: One-hundred and sixty-six patients did not undergo tonsillectomy (Group I, follow-up 130 ± 101 months) and 98 patients underwent tonsillectomy (Group II, follow-up 170 ± 124 months). The mean renal survival time was significantly longer for both end-points between those patients who underwent tonsillectomy (Group II) versus patients without tonsillectomy (Group I) (p Conclusion: Tonsillectomy may delay the progression of IgA nephropathy mainly in IgA nephropathy patients with macrohaematuria. Prospective investigation of the protective role of tonsillectomy in Caucasian patients is needed.Purpose: The role of tonsillectomy in the treatment of IgA nephropathy in Caucasian patients is controversial.Methods: A retrospective cohort study was conducted in 264 patients with biopsy-proven primary IgA nephropathy to examine the association between tonsillectomy and long-term renal survival, defined as the incidence of estimated glomerular filtration rates (eGFRs) of ≤30 ml/min/1.73 m2 or end-stage renal disease (the composite of initiation of dialysis treatment or renal transplantation). The association of tonsillectomy with renal end-points was examined using the Kaplan–Meier method and Cox models.",
keywords = "IgA nephropathy, Progression of IgA nephropathy, Tonsillectomy",
author = "Tibor Kov{\'a}cs and Tibor Vas and K{\"o}vesdy, {Csaba P.} and P{\'e}ter Degrell and Gy{\"o}rgyi Nagy and Zsuzsanna R{\'e}k{\'a}si and I. Wittmann and J. Nagy",
year = "2014",
month = "10",
day = "25",
doi = "10.1007/s11255-014-0818-7",
language = "English",
volume = "46",
pages = "2175--2182",
journal = "International Urology and Nephrology",
issn = "0301-1623",
publisher = "Springer Netherlands",
number = "11",

}

TY - JOUR

T1 - Effect of tonsillectomy and its timing on renal outcomes in Caucasian IgA nephropathy patients

AU - Kovács, Tibor

AU - Vas, Tibor

AU - Kövesdy, Csaba P.

AU - Degrell, Péter

AU - Nagy, Györgyi

AU - Rékási, Zsuzsanna

AU - Wittmann, I.

AU - Nagy, J.

PY - 2014/10/25

Y1 - 2014/10/25

N2 - Results: One-hundred and sixty-six patients did not undergo tonsillectomy (Group I, follow-up 130 ± 101 months) and 98 patients underwent tonsillectomy (Group II, follow-up 170 ± 124 months). The mean renal survival time was significantly longer for both end-points between those patients who underwent tonsillectomy (Group II) versus patients without tonsillectomy (Group I) (p Conclusion: Tonsillectomy may delay the progression of IgA nephropathy mainly in IgA nephropathy patients with macrohaematuria. Prospective investigation of the protective role of tonsillectomy in Caucasian patients is needed.Purpose: The role of tonsillectomy in the treatment of IgA nephropathy in Caucasian patients is controversial.Methods: A retrospective cohort study was conducted in 264 patients with biopsy-proven primary IgA nephropathy to examine the association between tonsillectomy and long-term renal survival, defined as the incidence of estimated glomerular filtration rates (eGFRs) of ≤30 ml/min/1.73 m2 or end-stage renal disease (the composite of initiation of dialysis treatment or renal transplantation). The association of tonsillectomy with renal end-points was examined using the Kaplan–Meier method and Cox models.

AB - Results: One-hundred and sixty-six patients did not undergo tonsillectomy (Group I, follow-up 130 ± 101 months) and 98 patients underwent tonsillectomy (Group II, follow-up 170 ± 124 months). The mean renal survival time was significantly longer for both end-points between those patients who underwent tonsillectomy (Group II) versus patients without tonsillectomy (Group I) (p Conclusion: Tonsillectomy may delay the progression of IgA nephropathy mainly in IgA nephropathy patients with macrohaematuria. Prospective investigation of the protective role of tonsillectomy in Caucasian patients is needed.Purpose: The role of tonsillectomy in the treatment of IgA nephropathy in Caucasian patients is controversial.Methods: A retrospective cohort study was conducted in 264 patients with biopsy-proven primary IgA nephropathy to examine the association between tonsillectomy and long-term renal survival, defined as the incidence of estimated glomerular filtration rates (eGFRs) of ≤30 ml/min/1.73 m2 or end-stage renal disease (the composite of initiation of dialysis treatment or renal transplantation). The association of tonsillectomy with renal end-points was examined using the Kaplan–Meier method and Cox models.

KW - IgA nephropathy

KW - Progression of IgA nephropathy

KW - Tonsillectomy

UR - http://www.scopus.com/inward/record.url?scp=84909602451&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84909602451&partnerID=8YFLogxK

U2 - 10.1007/s11255-014-0818-7

DO - 10.1007/s11255-014-0818-7

M3 - Article

C2 - 25181956

AN - SCOPUS:84909602451

VL - 46

SP - 2175

EP - 2182

JO - International Urology and Nephrology

JF - International Urology and Nephrology

SN - 0301-1623

IS - 11

ER -