Effect of the organic groups on the performance of hybrid silica based materials used as supports for biomolecules

Zoltán Dudás, L. Almásy

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Immobilization of biomolecules in porous supports, especially in silica matrices, is probably one of the most successful processes in biomaterials synthesis in the last three decades. The flexibility and versatility offered by the sol-gel process, ensured its leading position in the biomolecules immobilization. Functionalization with organic groups of the silica precursors leads to so-called organically modified silica gels. While there are many studies published recently about organically modified silica gels, the relationship between the functionalized support properties and the biomolecules activity is still poorly understood. The aim of this review is to summarize the available results on the influence of the organic functionalization of the silica support on the performance of immobilized biomolecules.

Original languageEnglish
Pages (from-to)2760-2767
Number of pages8
JournalCurrent Organic Chemistry
Volume21
Issue number27
DOIs
Publication statusPublished - Dec 1 2017

Keywords

  • Biomolecule encapsulation
  • Catalysis
  • Organically modified silica
  • Silica gels
  • Silica matrices
  • Sol-gel technique

ASJC Scopus subject areas

  • Organic Chemistry

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